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Mark Blenner

Thomas & Kipp Gutshall Career Development 

Professor, University of Delaware

NSF CREATE Biofoundry Director

Associate Chair of Chemical & Biomolecular Engineering

GAANN Inclusive Teaching in ChE Director

NIH & AHA Postdoc Fellow, Harvard Medical School

PhD Chemical Engineering, Columbia Univeristy
BS Chemical Engineering, Manhattan College

Dr. Blenner's interest is generating systems level data and synthetic biology tools to speed the design, build, test cycle for yeast, mammalian cells, and microbial communities. His group is interested in solving problems in complex environments, such as biomanufacturing, and wild environments outside the lab.

 

He views the most important part of his job as helping students develop as independent creative critical thinkers. Graduate students and typically create their projects under Dr. Blenner's guidance. 

 

Dr. Blenner has won numerous awards including the PECASE, the 2025 Langer Prize for Entrepreneurship and innovation, the 2022 Biochemical Engineering Journal Young investigator Aware,  2022 AIChE Division 15 Early Career Award, and the 2021 ACS BIOT Young Investigator Award.

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Graduate Students & Postdocs

Alli Adams, Ph.D.

Postdoctoral Fellow

Microbial Engineering &

Synthetic Biology

 

BS Chem Eng., LSU

PhD Chem Eng., WPI

Erik Breiling

PhD Student (w/ Kevin Solomon)

BVMO Engineering

BS Chem Eng., WPI

Matt Demelo

Postdoctoral Fellow

IEDH Fellow

Epigenetic Engineering

& Synthetic Biology

BS Chem. Eng., Georgia Tech

PhD, Systems & Synthetic Biology, Rice 

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Emily Doleh

PhD Student

GAANN Fellow

Gene Therapy Manufacturing & Synthetic Biology

BS Chem. Eng., Ohio State 

JT Gannon

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CBB PhD Student

T32 CBB Trainee

(w/ Chuming Chen)

AL/ML-enabled

Enzyme Engineering and Metabolic Engineering 

BS Biomed. Eng., UD

MS Bioengineering, UPenn

Could Be You

PhD Student

Awesome Research Topic

BS Chem. Eng., U of U

Samuel Fine

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PhD Student; CBI Fellow

(w/ Cathy Fromen)

Macrophage Engineering

& Synthetic Biology

BS Chem. Eng., Georgia Tech

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Phil Gitman

PhD Student

DE Space Grant Graduate Fellow; GAANN Fellow

Engineering Synthetic Methylotrophy

BS Chem. Eng., UConn

Laura Kirshenbaum

Microbiology PhD Student

NSF GRFP Honorable Mention

Engineering Downstream Recovery of Product 

BS Microbiology, Univ. of Nebraska

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Postdoctoral Fellow

Richa Guleria, PhD

Engineering Yeast for Space Biomanufacturing

BS Biochemistry, Garhwal University

PhD Biotechnology, Jawaharlal Nehru 

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PhD Student; GAANN Fellow

(w/ Kevin Solomon)

Alex Hansen

Microbiome of Plastic Degradation

BS Chem. Eng., UA Huntsville

Rachel Keown, PhD

Postdoctoral Fellow

Phage Engineering 

Metabolic Engineering of Yeast

BS, Biology, Acadia University

PhD Bioinformatics, UD

Michael Krausz

PhD Student (w/ Cathy Fromen)

Engineering Lactate-Specific

Epigenetic Modifications

BS Chem Eng, Georgia Tech

Derron Ma

PhD Student (w/ Wilfred Chen)

Acetyl-CoA Biosensor Control of Cellular Phenotype

BS Biosystem Eng, UC Davis

Chemistry PhD Student

CBI Fellow

Tristan Mabee

Microbial Community Engineering for Plastic Biodegradation

BS Chem Eng., UC Santa Barbara

PhD Chem. Eng., Princeton University

NSF GRFP

PhD Student

(w/ Kevin Solomon)

Nathan Miller

Microbial Community Engineering

BS Chem. Eng., Arizona State

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Microbiology PhD Student

DENIN Fellow

Austin Morgan

Autonomous Stable Gene Circuits

BS BIochem, Truman State

Pitch 90 Winner (2023)

Meredith Morse

PhD Student

(w/ Kevin Solomon)

NSF GRFP

Microbial Community Engineering

 

BS Chem. Eng., UMBC

Terra Miley

PhD Student

(w/ Wilfred Chen, Millie Sullivan)

NSF GRFP

TBD

BS Chem. Eng., UMBC

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Phil O'Dell

PhD Student

Yeast Metabolic Engineering of Plant Natural Products

BS Biochem, Miami University

MS Chem. Eng., Miami University

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PhD Student

CBI Fellow

Topher Pirner

Mammalian Synthetic Biology

BS Chem. Eng., Rose Hulman

Justin Roberts

PhD Student

Lineage Tracing in CHO Cells

 

BS Chem. Eng., WPI

Rachel Silvestri

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PhD Student

Yeast Engineering for

Protein Secretion

 

BS Chem. Eng., Manhattan College

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Anthony Stohr

PhD Student (w/ Wilfred Chen)

NDSEG Fellow

RNA-based Metabolic Biosensors

 

BS Chem. Eng., Northeastern

Frasier Russel Teaching Fellow 

Undergraduates

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Derek Consula

Class of 2028

Logan Impellizeri

Class of 2028 (Hum. Phys)

Aubryanna Jarchow

Class of 2029

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Susan Kuhn

Class of 2027

Ethan Lawrence

Class of 2029

Michael Machewirth

Class of 2029

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Ben McClaine

Class of 2027

Faiz Madiwale

Class of 2028 (Hum. Phys)

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Hamza Alam

Class of 2027

Class of 2030

Siddharth Athalye

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Class of 2028

Arnav Bedekar

Katherine Bell

Class of 2028

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Agni Miraji-Khot

Class of 2027

Rowan Moxley

Class of 2029

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Amelia Owen

Class of 2028

Manav Patel

Class of 2028

Rushil Rathod

Class of 2027

Raniya Robson

Class of 2028

Justin Stauffer

Class of 2028

Lucas Tillman

Class of 2028

Annika Warang

Class of 2028

Nicole Webb

Class of 2028

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Andrew Weismann

Class of 2028

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Abubakr Yousuf

Class of 2026

Lab Alumni

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Zhiliang Yang

Postdoctoral Fellow

(2019-20)

Engineering Yeast for Natural Product Biosynthesis

Currently seeking a faculty position.

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Weigao Wang

Graduate Student
(2015-21)

Enzyme & Secretion Engineering 

Currently a Postdoc at Stanford

 

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Allison Yaguchi

PhD Student
(2014-2020)

Aromatic metabolism in oleaginous yeast

Currently a Postdoc at NREL

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Charles Wang

MS Student
(2018-20)

Mammalian Artificial Chromosome

Currently at Unknown

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Difeng Gao

Postdoctoral Fellow (2015-18)

Yarrowia Metabolic Engineering

Currently at Biomedican, Inc.

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Murri Shabbir Hussain

PhD Student
(2013-2018)

Genetic Tools for Yarrowia

Currently at Abbott Biosciences

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Gabriel Rodriguez

Postdoctoral Fellow
(2014-17)

Yarrowia Metabolic Engineering 

Currently at Ginkgo Biosciences

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A. Nolan Wilson

PhD Student
(2009-14)

Metabolic Modeling

Currently at NREL

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Max Hilbert

PhD Student
(2018-2021)

Enzyme Immobilization

Currently at Unknown

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Molly Wintenberg

PhD Student
(2016-2022)

Microbial Radiation Biosensors

Currently NRC Fellow at NIST

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Mike Spagnuolo

PhD Student
(2015-2022)

Engineering Yeast for Biopolymers

Currently Postdoc in the Blenner Lab

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Dyllan Rives

PhD Student
(2016-2022)

ER Stress in CHO Cells

Currently Seeking a Position

Engineering Macronutrients from Plastic

BS Biophysics, Michigan

PhD Biophysics, Michigan

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Jason Karslake, PhD

Plastic Waste Upcycling

Currently at Molecular Templates

Postdoc

(2020-2022)

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Jyoti Singh, PhD

Postdoc

(2020-2022)

Microbiome Engineering & Plastic Biodegradation

Currently at Unilever 

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VIjay Ganesan

PhD Student

(2017-2023)

Genetic Tools for Pathway Balancing

Currently at Sandia National Lab

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Postdoc

(2023)

Michael Spagnuolo

Oleochemical Metabolic Engineering

Currently at US Army DEVCOM

Chris Nauman, PhD

Postdoc

(2021-2024)

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Engineering Macronutrientrs from Plastic

Sceintist, Siemans Healthcare

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Postdoc

(2022-2024)

Jaya Singh, PhD

Engineering Yeast for Oleochemicals

Postdoc in Eric Young Lab

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Postdoc

(2023-2024)

Patrick Beardslee, PhD

Engineering Yeast for Oleochemicals

Scientist, Mosaic Biosciences

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Ayushi Agrawal

PhD Student

(2019-2025)

Engineering Yeast for

Plant Natural Products

Postdoc, Napigen

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Prem Pratim, PhD

Metabolomics and Metabolic Engineering

Currently at TBD

Postdoc

(2022-2025)

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Ross Klauer

PhD Student

(2021-2025)

 Plastic Biodegradation

Currently at EnduraZymes

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Spencer Grissom

PhD Student

(2020-2025)

Genetic Tools for Pathway Balancing

Currently at Sandia National Lab

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Postdoc

(2023-2026)

Jenna Ott, Ph.D.

ASEE eFellows

Currently at TBD

Additional Lab Alumni

Delaware Students: Jacob Nicosia, Caleb Dinger, Magda Zdanowicz, Helena Hansen, Liv Quick, Neta Zilbershot, Shirly Gotlieb, Lauren DeSantis, Julia Jeskey, Eleanor Cook, Marisa Brown, Zach Dixon, Aidan Gensure, Caleb Lawson, Rena So, Megan Tarr,  Kayla Wolf, Hanna White, Mekhi Williams, Brian Sipko, Max Friedman, Dheeraj Pedada, Thanya Shemi, Zach Stevenson, Chiku Bhatt, Nick Brennan, Jack Seiffert, Khiem Le, Ian Kang, Suzi Zien, Jack Werb, Grace Shoemaker (UF), Bala Saravanan, Caroline Zu (Purdue), Gabriel Ma, Mugilan Nambi (High School), Brady Johnson, Kritee Sangroula, Joseph Castenda (CCNY), Grace Shoemaker (UF)Rainer Hlibok, Allie Platchek, Samanthan Burger, Audrey Cicerchia, Luis Garcia Osorio, Toni Akin Adenikan, Lydia Kowalski.

Clemson Students: Hayden Tharpe, Meredith Bailey, Taylor Cook, Erika Arvay, Lauren Gambill, Adam Beitz, Sarah Smith, Tatum Sass, Amy Rees, Julia Martone, Sierra Gurtler, Ahmad Alquza, Tara Richbourg, Scott Anglin, Dubby Wiseman, Sam Williams, Rachel Ham, Valarie Peters, Vaishnavi Kanduri, Mariana Holladay, Simon Ciprari, Jude de Konig, Will Burnette, Patrick Dayton, Chlo Forenzo, Cooper Tillman, Joel Watkins, David Kindervater, Matt Brabender, Brice Martin, Lane Norris, Tae Watts, Anna Delahunt, Sarah Dorsey, Sara Edgecomb, Samantha Hutter, Luke Mabry, Kaitlyn O'Neill, Melissa Nolan, Gabby Mochizuki, Caroline Peak, Mitchell Angove, Lexie Adams (Miami), Nicky Franaszek, Zach Williamson, Sean Miller, Morgan Usher, Mia Maciorowski, Cheyanne Brady, Camillo Susecum, Braxton Baird, Grant Smith, Peyton Hudson, Jennifer Cabezas, Sarah Smith, Jillian Laird, Danielle Acker, Elizabeth Huntley, Jenna Schoefield (MSU), Jack Tabb, Erin Mihealsick, Alana Robinson, Phillip Baker, Kaitlyn Scola, Robert Barrett, Vineeth Sama, Tanner Karp, Kylie Burkes, Caroline Moody (NCSU), Emma Ressler, Michael Xie (Ohio), Shanna Pearce, Will Hardy, Mary Kate Rumph, Tiffany Yu, Jeremy Fowler, Sarah Knowles, Parker Hume, Julia Borglin, Jessica Zielinski, Kyle Pazzo, Hayden Campbell, Justin James, Jacob Livingston, Jeanette Rodriguez, Meg Wilkes, Andrew Dippre, Joseph Whitaker, Charlie Kessler, Kyle Reed, Katie Stahel, Megan Stahlberger, Mohit Gahndi, Patricia Jokl, Joseph Redzikowski, James Foster, Thomas Pavelka, Lauren Reed, Thomas Stanton, Joy Jones, Dennish Parekh, Syed Bukhari, Yancy Appling, David Carey

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Cellular Engineering & Applied Synthetic Biology Lab

APBiopharm at UD STAR Campus

590 Avenue 1743, Rm 542-544

Newark, DE 19713

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